For example, tumor-specific and isoform-specific allelic expression patterns were observed for PLAGL1 (ZAC1, Additional file 17: Table S9; Additional file 18: Fig. S9) which encodes an important transcriptional factor and nuclear receptor co-activator, which is involved in cancer progression and resistance to treatment [1, 2, 8, 132]. This evidence concerns the gene PLAGL1 and cancer.