GPT and liver disorder: Adverse events of special interest that were more common than standard treatment (by at least 10 percentage points, all grades) were limited to hepatic events (hepatic disorders [n=44, 24%], biliary disorders [n=27, 15%], high ALT [n=48, 26%], and high bilirubin [n=43, 23%]; Hy's law biochemical criteria were met in two [1%] participants, of whom one died; table 4; appendix pp 50, 64–67).