PKD1 and autosomal dominant polycystic kidney disease: For example, it has been shown that Persian cats are susceptible to developing autosomal dominant polycystic kidney disease (ADPKD; MONDO:1011054) due to a variant in the polycystin 1, transient receptor potential channel interacting gene (PKD1, NCBIGene:100144606) [46, 47, 48].