CCR2 and HIV infectious disease: Our results showed that the CCR2-64I mutation has a possible protective effect on HIV transmission in the Angolan population (p < 0.001), with the heterozygous form (wt/mt) present in 80% of uninfected individuals compared to around 20% for infected individuals, while in the homozygous form (mt/mt), the mutation was present in 94% of uninfected individuals compared to 6% for infected individuals (Table 1), showing that the presence of the mutation may be playing an important role in the susceptibility to HIV infection in this population.