One subpopulation expressed CD44 + CXCR3 + CXCR4 + PRF1 + and GZM family genes, while the other expressed XCL1 + NCAM1 + GNLY + and KIR family genes, suggesting that these T cells possess a robust capacity to mediate tumor cell apoptosis. The gene discussed is CXCR3; the disease is neoplasm.