Notably, it has emerged as a promising alternative to antibiotics for treating urinary tract infections (UTIs) by inhibiting bacterial adherence to urothelial cells.[10] The mannose receptor (CD206 or Mrc‐1), predominantly found on macrophages (MΦ) and dendritic cells (DC), recognizes carbohydrates on the cell walls of pathogens.[11] Despite its significant role in biological processes, targeting the mannose receptor on MΦ has been explored mainly on nanoparticles functionalization for cancer‐related approaches.[12, 13]. Here, MRC1 is linked to urinary tract infection.