Analysis of the protein–protein interaction network in LRRK2 mutant organoids revealed a functional role for thioredoxin‐interacting protein (TXNIP) in the 3D environment of LRRK2‐associated PD, providing a theoretical basis for modeling sporadic PD based on organoids and advancing PD therapeutics.[182] Chlebanowska et al. This evidence concerns the gene TXNIP and Parkinson disease.