Last but not least, aberrant NEU1 expression has been implicated in numerous malignancies and is positively associated with poor prognosis (Figure S10a–c, Supporting Information).[56, 57, 58] Considering that an ideal therapeutic target for DIC should not only mitigate cardiac damage but also impede cancer progression, we further investigated the role of NEU1 in cancer chemotherapy. The gene discussed is NEU1; the disease is cancer.