This increased vascular sensitivity is found in the absence of differences in circulating ang II [11,15], although AT1R agonistic autoantibody (AT1-AA) concentrations, which are elevated during preeclampsia and contribute to a pro-constricted and anti-angiogenic milieu during preeclampsia [16,17], are also elevated postpartum [18-20]. Here, AGTR1 is linked to preeclampsia.