DEFB1 and colitis: Similar to in vivo colitis models, our analysis found that DSS+I3C treatment significantly increased the mRNA (Figures 2A,B,D,E) and protein expression (Figures 2C,F) of AhR and BD‐1 in CECs MC38 (Figures 2A–C) and Caco2 (Figures 2D–F) when compared to DSS alone, especially at higher doses of I3C.