To directly test if the expression of BD‐1 is regulated by AhR, we used murine adenocarcinoma cells, MC38, and human colon carcinoma, Caco2 cells which were treated with I3C at 0.1, 1 and 10 μm and then treated with DSS (0.03%) for additional at 8, 16, and 24 h, to assess their impact on AhR expression in MC38 and Caco‐2 cells (data not shown). This evidence concerns the gene AHR and adenocarcinoma.