B2M and neoplasm: The present literature also shows a gap regarding evaluation process, advising that future studies should include most accurate instruments to address disease parameters: physical exam and health history, complete blood count, blood chemistry studies, lactate dehydrogenase testing, beta-2-microglobulin testing, flow cytometry to quantify tumour markers at cell surface, FISH analyses, gene mutation testing, serum immunoglobulin testing, chest x-ray for organs and bones, CT scan and/or PET-CT scan.