Nowadays, there are more and more studies on m6A in PCOS, but except for the major m6A proteins METTL3, FTO, YTH family, the rest of the regulatory factors, such as METTL14 and ALKBH5, are less studied and not much clinically translated, so there is still an emergent need to explore the role of other m6A-related proteins or investigate the long-term effects of m6A-targeted therapies. The gene discussed is METTL3; the disease is polycystic ovary syndrome.