To corroborate that TGFα was a relevant factor in the regulation of pancreatic cancer cell proliferation, we eliminated its expression by CRISPR/Cas9 in three of the pancreatic cancer cell lines (Fig. 2C), and two clones of each cell line were selected to assess the effect of TGFα loss on cell proliferation. The gene discussed is TGFA; the disease is pancreatic neoplasm.