A transcriptomic profiling analysis of trophoblast isolated from gestational diabetes mellitus (GDM) defined 8 ubiquitin-conjugating enzymes (UBE) splice variants (UBE2D3 variants 1, 3, 4, 5, 6, 7, 9 and UBE2V1 variant 4) are associated with increased maternal fasting plasma glucose (Kim et al. 2013). Here, UBE2V1 is linked to gestational diabetes.