We also examined normalised p53 aggregate concentrations in homogenised tumour tissue and observed no difference between patients with mutant TP53 (n = 10) and WT TP53 (n = 10) (Mutant vs WT (Median (IQR)): 224.596 (44.317, 1244.809) vs 126.025 (46.021, 425.174), Mann–Whitney U-test p value = 0.473) (Supplementary Fig. S7a). This evidence concerns the gene TP53 and neoplasm.