Epigenetic dysregulation of the imprinting genes identified is not only related to obesity but also to diseases including paternal uniparental disomy (BLCAP (cg01466133, cg07156273, cg10981598, cg14469070, cg18433380, cg23605670), NAP1L5128 (cg11300971, cg01026744), MEG3 (cg08698721), NNAT (cg11174847) and Down’s syndrome (BLCAP (cg07156273, cg10981598, cg14469070), VTRNA2-1 (cg00124993, cg06536614, cg25340688 and cg26896946)) in the EWASAtlas (Supplementary Data 11). Here, MEG3 is linked to obesity due to melanocortin 4 receptor deficiency.