For VTRNA2-1, all four dmCpGs (cg00124993, cg06536614, cg25340688 and cg26896946) were linked with Down’s syndrome, Parkinson’s disease and breast cancer, while three were linked with gestational diabetes, Clopidogrel resistance, and glycaemic response to glucagon-like peptide-1 analogue therapy in type 2 diabetes mellitus (Supplementary Data 11: ImprintedGene_EWAStraits). The gene discussed is GCG; the disease is Down syndrome.