The results of CD8 + T cells cytotoxicity assay revealed that high expression of USP8 could promote the immune evasion of DU145 and PC-3 PCa cells while low expression of USP8 could inhibit the immune evasion of DU145 and PC-3 PCa cells (Fig. S4G, H). This evidence concerns the gene USP8 and posterior cortical atrophy.