GREM1 and discoid lupus erythematosus: Importantly, these GREM1+ fibroblasts were consistently present across CLE subtypes, including both subacute cutaneous lupus (SCLE) (Figure 4D-F) and discoid lupus erythematosus (DLE) (Supplementary Figure S6), with the same localization, associated chemokines (CXCL10, CCL5), and associated cell types (pDC, T cells).