F2RL1 and viral infectious disease: SB3 is in fact able to induce the activationof protease-activated receptor 2 (PAR2), a membrane receptor able to regulate host cell interferon and inflammatorycytokines., Indeed, PAR2 has been describedas an important host factor in other crucial viral infections, suchas influenza A, where it has been shown to inhibit the antiviral responseand enhance the inflammatory response.−,