Another ChIP study involving H3K4me3, H3K27me3, H3K9me3, H3K9Ac, and H4K16Ac showed elevated levels of H3K9Ac in T1DM-susceptible genes—such as HLA-DRB1 (HLA class II histocompatibility antigen, DRB1 β chain) and HLA-DQB1—in T1DM patients compared to a healthy cohort [94]. The gene discussed is HLA-DQB1; the disease is type 1 diabetes mellitus.