The visual field mean deviation in our glaucoma group was mean -5.72dB (standard deviation 2.67dB) which represents moderate loss, but is still less than half of the mean in Kankipati et al. [5] or the “Late” group in Adhikari et al. [7] A further histological study found melanopsin-based RGC loss in severe glaucoma eyes, but not in early glaucoma eyes post-mortem [3]. The gene discussed is OPN4; the disease is glaucoma.