For instance, the HLA-DRB1*01 haplotype is positively associated with oligoarticular JIA, whereas oligoarticular and poliarticular JIA share a strong association with the HLA-DRB1*08 haplotype, and enthesitis-related JIA is associated with the HLAB27 haplotype [4, 35–38]. Here, HLA-DRB1 is linked to juvenile idiopathic arthritis.