Finally, we observed higher median IL-2 levels in CE3b patients compared to controls in response to the AgB1 pool (median 43.80 pg/mL, IQR: 28.10–100.1 vs. 2.74 pg/mL, IQR: 1.1–7.5) and AgB total pool (median 101.2 pg/mL, IQR: 65.1–134.6 vs. 22.9 pg/mL, IQR: 11.1–45.9) (p = 0.0016 and p= 0.0031, respectively), and a higher IL-13 level in response to the AgB total pool in patients with CE3b and CE4/CE5 cysts compared to NO CE subjects (p = 0.0016, median 9.00 pg/mL, IQR: 4.5–11.8 vs. 0 pg/mL, IQR: 0–2.3; p = 0.0009,median 9.3 pg/mL, IQR: 4.3–15.5 vs. 0 pg/mL, IQR: 0–2.3) (Figure 3B,C). The gene discussed is IL2; the disease is cholesteryl ester measurement.