IGF1R and breast cancer: For instance, miR-143 is a constituent of the moderately intricate EC ceRNET depicted in Figure 2C. In 2017, Wang and collaborators showed that, in bladder cancer (BC), miR-143 is a functional repressor of IGF-1R [218] that, in our EC ceRNET, is present in Figure 1 (coordinates: j8) and exhibits the above-mentioned characteristics of robustness.