Indeed, BDNF levels in patients treated with MC (median value 1672.6 pg/mL) were higher than BDNF levels in both healthy subjects (167.1 ± 171.2 pg/mL) and in patients with fibromyalgia (113.8 ± 149.6 pg/mL), as reported in the literature [38]. This evidence concerns the gene BDNF and fibromyalgia.