Kaiso regulates Wnt/β-catenin target genes, including Wnt11, Cyclin D1, and Matrilysin 7, in various cancers (33, –, 35), but these were absent in classical VN and VP-MCC cell lines, while variant MCC cells expressed only Cyclin D1 (data not shown). This evidence concerns the gene WNT11 and Merkel cell skin cancer.