Within the core region, Iba1 immunoreactivity was more strongly increased in animals given acute NPC treatment compared with those treated later; however, the difference did not reach statistical significance (ibz: NPCacute: +18.8%, NPCdelayed: +8.4%, p = 0.34; core: NPCacute: +86.8%, NPCdelayed: +13.5%, p = 0.11). The gene discussed is AIF1; the disease is nasopharyngeal carcinoma.