MT2A and neoplasm: MT2A belongs to the super-family of low-weight intracellular metallothioneins.23,24 Innovative evidence has illustrated the differential expression status of MTs in various tumors, and the vital roles of MTs in tumor formation, cell growth, and metastasis.25 For MT2A, this isoform of MTs presents a differential expression depending on the type and differentiation status of tumors.