To further investigate the prognostic significance of various clinicopathological factors, we conducted univariate survival analyses for cancer-specific survival in LUSC patients (Figure 2a, Table 2), with a focus on various clinicopathological variables including age, sex, differentiation grade, tumor site, laterality, tumor size, T stage, N stage, and MXD3 expression levels. The gene discussed is MXD3; the disease is neoplasm.