The aim of this study is to investigate possible CBD neuroprotective effects in the development of parkinsonism induced by low-dose repeated reserpine, using two approaches: (1): administering CBD concurrently with the development of parkinsonism (concomitant treatment), and (2) using CBD as a preventive treatment before the induction of the parkinsonian alterations (preventive treatment). This evidence concerns the gene OPN1MW and Parkinsonism.