Regarding the association between the analyzed variables with pCR, a multivariate logistic regression analysis showed that the use of the ACTH regimen was significantly associated with achieving pCR [OR = 2.43; 95% CI = 1.13 - 5.24; p = 0.023], as was the presence of HER2 receptor in tumor's immunohistochemistry [OR = 2.49; 95% CI = 1.14 - 5.86; p = 0.028] (Table 3). The gene discussed is POMC; the disease is neoplasm.