Among women with hyperprolactinemia (30 women), 73.4% had tumor etiology (14 women with microadenoma and 8 women with macroadenoma) and 26.6% had idiopatic etiology, 76.7% were using dopamine agonists, and the median of prolactin value was 40.0 ng/mL. The gene discussed is PRL; the disease is neoplasm.