But, sexual desire can also diminish in women with increased serum prolactin levels, due mainly to relevant complaints, associated with decreased lubrication and orgasm.(2) Hyperprolactinemia impairs sexual function, leading to deficient luteal phase of the menstrual cycle, and chronic anovulation, resulting in a negative impact on female reproductive life.(3) Most studies assesses the impact of hyperprolactinemia in men's sexual function, but there is evidence of the correlation between prolactin levels and post orgasmic sexual arousal in both sexes.(4). This evidence concerns the gene PRL and hyperprolactinemia.