Preclinical studies have demonstrated that TCM and its active constituents can inhibit the proliferation of ovarian cancer cells, promote apoptosis, reverse drug resistance, and modulate key oncogenic signaling pathways, including PI3K/Akt/mTOR, Wnt/β-catenin, Notch, NF-κB, and MAPK pathways (24–28). The gene discussed is AKT1; the disease is ovarian cancer.