Noteworthy findings include significant differences in cytokine profiles between BALF and blood, with elevated levels of key inflammatory markers like IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-17, IFN-α, IFN-γ, TNF-α, and TNF-β in BALF indicating a localized inflammatory response in children with LC. This evidence concerns the gene TNF and laryngotracheoesophageal cleft.