The results showed that C0 IGLC3+ myeloma cells had the highest differentiation potential, indicating that C0 IGLC3+ myeloma cells had the strongest proliferation ability and were naive tumor cells, followed by C1 IGHA1+ myeloma cells, C2 IGHG1+ myeloma cells, and C3 IGHG4+ myeloma cells (Figures 4A, B). The gene discussed is IGHG4; the disease is plasma cell myeloma.