Finally, we analyzed the metabolic characteristics of myeloma cell subsets, and found that the expression level of Oxidative phosphorylation was higher in C0 IGLC3+ Myeloma cells and C3 IGHG4+ Myeloma cells, while the expression levels of Drug metabolism-cytochrome P450 and Drug metabolism-other enzymes were more active in C0 IGLC3+ Myeloma cells. The gene discussed is IGHG4; the disease is plasma cell myeloma.