Based on the cell lineage developmental characteristics, GO BP enrichment analysis was performed, and C0 IGLC3+ Myeloma cells were enriched in alphabeta immune mediated leukocyte, immunity differentiation activation and antigen lymphocyte pathways, C3 IGHG4+ Myeloma cells were enriched in subunit ribosomal, biogenesis, riponucleoprotein and translational translaton pathways, and C2 IGHG1+ Myeloma cells were enriched in blood pressure, arterial systemic and reninangiotensin and other related pathways (Figure 4Q). Here, IGHG4 is linked to plasma cell myeloma.