ADRB1 and esophageal squamous cell carcinoma: In order to examine the role of ADRB1+ T cells in the clinical prognosis of patients before and after neoadjuvant therapy, we intersected the genes up-regulated by ADRB1+ T cells after treatment with the genes of the adrenergic receptor signaling pathway, and then calculated the risk scores of ESCC patients in the TCGA data using ssGSEA (Supplementary Table 4).