M6A-related proteins such as METTL3 and METTL14 have been reported to increase follicle-stimulating hormone (FSH) levels while decreasing luteinizing hormone (LH) and testosterone (T) levels in PCOS rats, thereby reducing apoptosis and autophagy in ovarian tissue and improving ovarian morphology (115). This evidence concerns the gene METTL3 and polycystic ovary syndrome.