CD4 and juvenile idiopathic arthritis: As CD4 Naïve, CD4 TCM, CD8 Naïve, and CD8 TEM were shared T cell subtypes among patients with JIA, pSS, and SLE, we analyzed the upregulated DEGs specific to these four T cell subtypes, comparing JIA with cHC, pSS with aHC, and SLE with aHC, respectively (Figure 4C).