Bioinformatics analysis showed that the gene expression of IGF2BP3 was increased in RA synovial tissue, while TP can decrease the expression of IGF2BP3 in human PBMC and MH7A, so IGF2BP3 may serve as a prospective target for the therapeutic effect of TP on RA (23). The gene discussed is IGF2BP3; the disease is rheumatoid arthritis.