It is characterized as a single-pass transmembrane receptor comprising an extracellular domain, transmembrane and juxtamembrane regions, and a tyrosine kinase domain (16). In cancer, aberrant MET signaling contributes to tumor invasion and regulates various physiological processes, including embryogenesis, wound healing, liver regeneration, angiogenesis, and immunomodulation (17–20). Here, NRP1 is linked to cancer.