ANRIL has been shown to regulate its neighboring Cyclin Dependent Kinase Inhibitor genes, CDKN2A and ‐B, but little is known about their role in myocardial ischemia (Cho et al., 2019; Kotake et al., 2011; Yap et al., 2010). The gene discussed is CDKN2A; the disease is myocardial ischemia.