The closest protein‐coding genes neighboring the 9p21.3 CAD risk interval are the cell cycle regulators and tumor suppressors MTAP, CDKN2A, and CDKN2B, which play an important role in cell cycle regulation and inhibition of cell proliferation (Krimpenfort et al., 2007; Kryukov et al., 2016; Zhao et al., 2016). This evidence concerns the gene CDKN2A and coronary artery disorder.