9p21.3 CAD risk locus and its lncRNA transcript ANRIL have been identified as a hotspot for CAD and MI associated SNPs (Burd et al., 2010; Helgadottir et al., 2007; Holdt et al., 2016; McPherson et al., 2007; Samani et al., 2007; The Wellcome Trust Case Control Consortium, 2007; Tibaut et al., 2022). This evidence concerns the gene CDKN2B-AS1 and coronary artery disorder.