CDKN2B-AS1 and coronary artery disorder: While variation in the 9p21.3 locus and ANRIL expression have been associated with the risk of MI in some studies, other studies focused on patients with established CAD have revealed no significant link between the 9p21.3 genotype and CAD outcomes, including MI (Cheng et al., 2017; Haslacher et al., 2016; Horne et al., 2008; Patel et al., 2014, 2019; Tibaut et al., 2022).