Furthermore, 62 out of the 115 genes were expected to have high expression levels in TCGA HCC samples (Fig. S7G), including COL1A1, LOXL2, CCNB2, STC2, KIF11, CD34, CDK1, and COL4A1, which were reported as oncogenic genes to HCC development [80–82] and also associated with shorter survival (such as CCNB2, SLC1A4) (Fig. 6H and Fig. S7H). Here, LOXL2 is linked to hepatocellular carcinoma.