Furthermore, these 336 gene expression patterns in 45 HCC samples compared with 20 CHB samples were detailly displayed (Fig. 4F, left) and top 54 genes were also presented (Fig. 4F, right), including well-known prognostic biomarkers of HCC such as KIF11, CCNA2, CDK1, and CCNB2 [68, 69]. This evidence concerns the gene KIF11 and hepatocellular carcinoma.