CD4 and rheumatoid arthritis: Regarding clinical parameters, a positive association between the inflammatory activity of the RA and the proportion of Th1 cells (IFNγ+CXCR3+CD4+ T cells, regression coefficient 0.07, p = 0.003) and a negative association between age and TREC counts (regression coefficient -0.066, p = 0.003) was found.