REL and Hodgkins lymphoma: We identified several CNVs that are known recurrent events in HL, including an amplification of JAK2 and the neighboring PD-L1 and PD-L2 genes (9p23-p24) in the HL of case 1, and a REL amplification (2p13) in the HL of case 4 (Fig. 2, and Supplementary Fig. 6).