The groups in question here are as follows: PD patient samples with double mutations (carriers), PD LRRK2 mutation-positive, PD PRKN biallelic, PD PRKN monoallelic, non-PD controls, non-PD controls the female surplus group, DLB individuals, and the Mito group. The gene discussed is LRRK2; the disease is Lewy body dementia.