CD4 and neoplasm: In parallel, CD4+/CD8+ CXCR5+T follicular helper cells and CD8+CD103+ tissue-resident memory T cells were observed infiltrating in tumor tissues (Fig. 3f), Moreover, CD200 expressing B (CD20+CD200+) and T cells (CXCR5+CD200+) accumulated in the DCB groups (Fig. 3g).