These results underscore the crucial role of mitochondria in resolving inflammation and facilitating tissue repair through the modulation of efferocytosis and interaction with fibroblasts, holding significant potential for improving post-MI recovery and addressing other inflammatory conditions.602 The mitochondrial deacetylase Sirtuin3 (Sirt3) plays a crucial role in regulating metabolic and antioxidant functions linked to hypertension. The gene discussed is SIRT3; the disease is Hypertension.