Although compared with SD rats, SDT-f rats exhibited larger kidney weight; higher BUN, urinary albumin excretion (UAE), total cholesterol, triglycerides, HDL-cholesterol, and plasma insulin; and increased kidney injury molecule-1–positive (KIM-1+) cells, there were no significant differences in kidney lipid accumulation, plasma free carnitine, short-chain Acyl-C, middle-to-long-chain Acyl-C, ratio of short-chain Acyl-C/middle-to-long-chain Acyl-C, expression levels of collagen in the kidneys, or glomerulosclerosis between the 2 groups (Figure 3, D–N, and Supplemental Table 1). Here, INS is linked to glomerulosclerosis.