The NF1 mutation may also be related to some neurodevelopmental disorders such as cognitive impairment of the speech and motor system, Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), dyslexia, as well as other clinical features such as epilepsy and chronic headache (migraine) (North et al., 1997; Hyman et al., 2005; Pecoraro et al., 2017; Vogel et al., 2017). Here, NF1 is linked to attention deficit-hyperactivity disorder.