A 5-biomarker panel, consisting of the mutational targets APC, Bat-26, KRAS, L-DNA, and p53 by Ahlquist et al., achieved a high performance for overall CRC detection with 91.0% (20/22) sensitivity and 93.0% (26/28) specificity, with an APL detection rate of 82.0% (9/11) [38]. The gene discussed is KRAS; the disease is colorectal carcinoma.