Two recent biomarker panels incorporating methylated LASS4, LRRC4, PPP2R5 C, ZDHHC1, and Haemoglobin demonstrated strong overall CRC detection, with sensitivities of 93.0–95.2% and specificities of 88.5–89.8% [49, 51]. The gene discussed is LRRC4; the disease is colorectal carcinoma.